Vaccine Filtration - Enhancing Efficiency

This case study looks at a French pharmaceutical company that sought to enhance vaccine filtration processes in biopharmaceutical production by implementing METTLER TOLEDO Pendotech’s PM2 photometer. The PM2 instrument enables real-time, in-line measurement of turbidity and UV absorbance at 280 nm, essential parameters for monitoring the clarity and protein content of solutions during filtration steps. The company aimed to ensure vaccine filtration efficiency and maintain product integrity, critical factors in vaccine manufacturing. 

Traditional off-line turbidity measurements are time-consuming and provide delayed results. By integrating the PM2 photometer directly into the filtration line, the manufacturer could continuously monitor turbidity in real time, allowing rapid detection of any deviations or contaminants.